Learn more about the Tohono O'odham Nation, also known as the 'People of the Desert,' through exhibits and educational programs at the Tohono O'odham Nation Cultural Center and Museum. With about 28,000 members, and a land base approximately the size of the state of Connecticut-spanning just south of Casa Grande in central Arizona to the border of Mexico-the Tohono O'odham Nation is the second-largest American Indian tribe in the state. Visit the Tohono O'odham Nation to see a rich culture alive and well, flowing through the communities west of Tucson.